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Home > West Medicine > ENT & Ophthalmology > Stomatology
L10.000

Pemphigus Vulgaris

口腔科

Common symptoms

黏膜损害、手表皮深处的水疱、口咽部水疱状损害

The pathology of disease

Pemphigus vulgaris is autoimmune intraepidermal blistering disease (anti-desmoglein 3/1), presenting with flaccid bullae/erosions on skin/mucosa (oral erosions common). Treatment: systemic corticosteroids (prednisone); steroid-sparing immunosuppressants (azathioprine/mycophenolate mofetil); rituximab (first-line in many protocols); IVIG; wound care; oral care; infection prevention; monitor for steroid complications; follow-up dermatology.

Common Symptoms

Flaccid bullae/erosions; oral erosions; skin; autoimmune

Causes and Pathogenesis

Autoantibodies against desmoglein cause acantholysis and intraepidermal blisters.

Treatment

Systemic steroids; azathioprine/mycophenolate; rituximab; wound care

Preventive Measures

Early diagnosis; infection prevention; monitor drug side effects.

Department to Visit

It is recommended to visit the Dermatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.