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Home > West Medicine > Pediatrics > Pediatric Internal Med

Classroom classification

百科

Infantile cortical hyperostosis

儿科综合

Common symptoms

持续性发热、烦躁不安、软组织肿胀

The pathology of disease

Infantile cortical hyperostosis (Caffey disease) is infantile cortical thickening; mandible/ulna/clavicle; irritability; fever; SWAT1 mutation; self-limited.

Symptoms

Irritable infant; soft tissue swelling over mandible/long bones; fever; painful; cortical thickening on x-ray

Causes

COL1A1 mutation; autosomal dominant; cortical hyperostosis.

Treatment

NSAIDs; supportive; self-limited over months; usually resolves

Dept

Pediatrics / genetics / orthopedic.

Warm reminder: Health education reference only; seek care at regular hospital.

Family room

儿科综合Overview of the Western Medical Room