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Home > West Medicine > Other Specialties > Dermatology
L10.200

Pemphigus Foliaceus

皮肤科

Common symptoms

黏膜损害

The pathology of disease

Pemphigus foliaceus is superficial subcorneal blistering (anti-desmoglein 1), presenting with scaly crusted erosions on seborrheic areas (face/scalp/chest), no mucosal involvement. Treatment: topical/systemic corticosteroids; steroid-sparing agents (dapsone/azathioprine/mycophenolate); rituximab for severe; wound care; monitor for progression to PV; avoid triggering drugs (penicillamine/ACE inhibitors); follow-up.

Common Symptoms

Scaly crusted erosions; seborrheic areas; no mucosal involvement

Causes and Pathogenesis

Anti-desmoglein-1 antibodies cause superficial subcorneal acantholysis.

Treatment

Topical/systemic steroids; steroid-sparing; rituximab; wound care

Preventive Measures

Early diagnosis; avoid trigger drugs; skin care.

Department to Visit

It is recommended to visit the Dermatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.