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Home > West Medicine > Other Specialties > Dermatology
A58.x00

Granuloma Inguinale

性病科

Common symptoms

丘疹、淋巴结肿大、驻站医、色素脱失、肉芽肿、浆液脓性分泌物

The pathology of disease

Granuloma inguinale (donovanosis) is a chronic mildly contagious STD caused by Klebsiella granulomatis. In infected tissue the organism appears as intracellular oval bodies (Donovan bodies). It features granulomatous plaques, painless ulcers on anogenital sites, and autoinoculation.

Common Symptoms

Papule; lymphadenopathy; station doctor; depigmentation; granuloma; seropurulent discharge

Causes and Pathogenesis

Besides sexual transmission, it can be spread by Phthirus pubis; besides genital/femoral sites it may involve face/back. K. granulomatis is pathogenic only to humans. At the portal it first forms a slowly progressive papule/subcutaneous nodule, then an ulcer extending to surrounding tissue; pathology is dense inflammatory infiltrate.

Treatment

Drug therapy, supportive therapy

Preventive Measures

Complete treatment; return for follow-up; avoid sex until both patient and partner are cured; use condoms. Sex partners within 60 days of symptom onset should be examined/treated. Avoid promiscuous sex.

Department to Visit

It is recommended to visit the STD department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.