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Home > West Medicine > Other Specialties > Oncology
百科

Non-Hodgkin lymphoma

肿瘤内科

Common symptoms

淋巴结肿大、纵膈淋巴结肿大、骨痛、盗汗、腹痛、颅内压增高、消瘦

The pathology of disease

Non-Hodgkin lymphoma (NHL) is a large group of malignant lymphomas; far more common than Hodgkin disease in China. Incidence rising. More heterogeneous than HD; lower cure rate. Course variable; 50% pediatric/20% adult develop leukemia-like changes.

Common Symptoms

Lymphadenopathy; mediastinal lymphadenopathy; bone pain; night sweats; abdominal pain; ICP; weight loss

Causes

Chromosomal abnormalities; immunodeficiency (PIDS/HIV/transplant). T-cell vs B-cell markers (CD4/CD8/CD10/CD19/CD20/CD21, surface Ig). B-cell stages: pre-B (TdT+, heavy chain rearrangement) → immature (IgM) → mature (IgD/IgM) → plasma cell (PC-1/PC-2). Follicular vs diffuse.

Treatment

Drug therapy; supportive care

Prevention

Exercise; avoid infection/radiation/toxins/immunosuppressants.

Recommended Department

It is recommended to visit the oncology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.