Renal Glycosuria

Renal glycosuria is a benign proximal renal-tubular defect causing impaired glucose reabsorption, with glucose in urine despite normal blood glucose. It is usually asymptomatic and found incidentally; may be familial or acquired. It must be distinguished from diabetes mellitus (normal blood glucose/HbA1c). No specific treatment; monitor for potential volume depletion and distinguish from Fanconi syndrome.

Common Symptoms

Glucose in urine; normal blood glucose; usually asymptomatic; polyuria rarely

Causes and Pathogenesis

Reduced SGLT2-mediated proximal-tubular glucose reabsorption causes urinary glucose loss with normal serum glucose.

Treatment

Usually no treatment needed; confirm normal glucose tolerance; distinguish from diabetes/Fanconi

Preventive Measures

Distinguish from diabetes; monitor electrolytes.

Department to Visit

It is recommended to visit the Nephrology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.