Chronic Fibrous Thyroiditis (Riedel)

Riedel thyroiditis is a rare chronic fibrous thyroiditis in which the thyroid is replaced by hard, woody fibrotic tissue extending beyond the capsule into surrounding structures. It causes compressive symptoms (dyspnea, dysphagia, hoarseness), painless hard fixed goiter. Associated with IgG4-related disease and other fibrosing conditions. Hypothyroidism may occur; treatment: tamoxifen/steroids; isthmusectomy for decompression.

Common Symptoms

Painless hard fixed woody goiter; dyspnea; dysphagia; hoarseness; compressive symptoms; hypothyroidism

Causes and Pathogenesis

IgG4-related fibro-inflammatory process destroys thyroid parenchyma and extends into neck structures; dense fibrosis with occlusive phlebitis.

Treatment

Corticosteroids; tamoxifen; mycophenolate; isthmusectomy for decompression; L-thyroxine replacement

Preventive Measures

Early diagnosis; evaluate other IgG4-related fibrosing conditions.

Department to Visit

It is recommended to visit the Endocrinology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.