Locked-lung Syndrome

Locked-lung syndrome is severe asthma with extensive mucus plugging and poor response to beta-agonists, presenting with acute severe dyspnea, wheeze, and airflow obstruction despite therapy. Treatment: oxygen; systemic corticosteroids; humidified air; bronchoscopy to suction mucus plugs; IV magnesium; ICU; mechanical ventilation if needed; treat infection triggers; avoid overhydration; monitor closely.

Common Symptoms

Severe dyspnea; poor beta-agonist response; mucus plugging; hypoxemia

Causes and Pathogenesis

Extensive mucus plugging of airways causes severe airflow obstruction refractory to bronchodilators.

Treatment

Oxygen; systemic steroids; bronchoscopic mucus clearance; magnesium; ICU/ventilation if needed

Preventive Measures

Asthma controller adherence; hydrate; treat infections early.

Department to Visit

It is recommended to visit the Pulmonology-Emergency/ICU department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.