医
China Med Service
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淋巴结肿大、流感样症状、呼吸困难、结节、咯血、盗汗、肺纤维化、低热
Pulmonary histoplasmosis capsulati is the pulmonary manifestation of Histoplasma capsulatum infection; primary pulmonary, usually asymptomatic/self-limited; severe = disseminated mainly to reticuloendothelial system.
Lymphadenopathy; flu-like symptoms; dyspnea; nodule; hemoptysis; night sweats; pulmonary fibrosis; low fever
Etiology: dimorphic H. capsulatum; mycelial in soil, yeast in host (pseudocapsule). Inhaled spores → alveolar replication → yeast form → neutrophils/macrophages; yeasts survive in macrophages → hilar nodes → blood. 2-3 weeks later CMI kills fungi → granuloma/caseous necrosis; immunocompetent = pulmonary limited; immunosuppressed/high inoculum = progressive disseminated. Healing = calcification/fibrosis. Diagnosis: epidemiology/clinical/X-ray/serology; confirm by culture/histology.
Drug therapy, supportive therapy
Laboratory precautions; new arrivals to endemic areas; bird droppings/bat caves contaminated. 3% formaldehyde disinfection; prophylactic antifungals.
It is recommended to visit the Respiratory department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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