Apical Hypertrophic Cardiomyopathy

Apical hypertrophic cardiomyopathy is hypertrophy confined to the left-ventricular apex (Yamaguchi syndrome), often presenting with deep T-wave inversion on ECG and apical hypertrophy on echo/MRI. It is often benign but may cause chest pain/arrhythmia. Treatment: beta-blocker/verapamil for symptoms; treat arrhythmias; ICD in selected high-risk; prognosis generally good; long-term follow-up.

Common Symptoms

Often asymptomatic; chest pain/palpitations; deep T-wave inversion; apical hypertrophy on echo/MRI

Causes and Pathogenesis

Sarcomere mutation causes hypertrophy localized to the LV apex.

Treatment

Beta-blocker/verapamil for symptoms; treat arrhythmias; ICD in selected high-risk; follow-up

Preventive Measures

Family screening; long-term echo/ECG follow-up.

Department to Visit

It is recommended to visit the Cardiology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.