医
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面颊及上胸部充血、发烧、腹泻、反复呕血、鼻出血
OHF is an acute febrile viral zoonosis with bleeding signs and benign course. Recognized 1941-43; first reported in northern Omsk, Siberia (1944-45); outbreaks in 1945/46 (200+/600+ cases).
Flushed face/upper chest; fever; diarrhea; recurrent hematemesis; epistaxis
(1) Etiology: Flavivirus (Togaviridae), +ssRNA, neurotropic; CPE in Hela/chick embryo/hamster kidney/monkey kidney cells; isolated from acute blood and Dermacentor ticks. (2) Pathogenesis: vascular damage, thrombocytopenia, bleeding in brain/kidney/endocardium/myocardium/GI. Targets vessels/nervous system; endothelial damage → permeability/edema/brain edema → sensory changes; vasomotor collapse/shock; Kupffer-cell hemosiderin.
Drug therapy, supportive therapy
Tick control and personal protection. Effective live attenuated vaccine exists but side effects limit use.
It is recommended to visit the Infectious Diseases department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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