Autoimmune Pancreatitis

Autoimmune pancreatitis is fibroinflammatory pancreatic disease (type 1 IgG4-related / type 2 idiopathic duct-centric), presenting with painless jaundice, pancreatic mass, elevated IgG4, and diffuse/focal enlargement on imaging. Treatment: corticosteroids (prednisone) induction; azathioprine/immunomodulators for relapse/steroid-dependent; monitor IgG4/labs/imaging; treat associated IgG4-related disease (sialitis/retroperitoneal fibrosis/cholangitis); differentiate from pancreatic cancer; long-term follow-up for relapse/complications.

Common Symptoms

Painless jaundice; pancreatic mass; elevated IgG4; diffuse/focal enlargement

Causes and Pathogenesis

IgG4-related immune reaction causes storiform fibrosis and obliterative phlebitis.

Treatment

Corticosteroids; immunomodulators for relapse; monitor IgG4/imaging

Preventive Measures

Early diagnosis; monitor associated IgG4 disease.

Department to Visit

It is recommended to visit the Gastroenterology/Hepatobiliary-surgery/Rheumatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.