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无力、胸痛、胃肠道症状、呼吸困难、腹泻、衣玉品、腹痛、便秘、低热、恶心、厌食
Whipple disease is systemic infection by Tropheryma whipplei, affecting small bowel (malabsorption), joints, CNS, and heart, presenting with diarrhea, weight loss, arthralgia, and fever. Treatment: prolonged antibiotics (initial ceftriaxone, then TMP-SMX or penicillin for 12+ months); nutritional support; treat complications (endocarditis/neurologic involvement); monitor for relapse; follow-up PCR/endoscopy; prolonged treatment to prevent CNS relapse.
Diarrhea; weight loss; arthralgia; fever; by T. whipplei
Bacterial infection causes macrophage infiltration of small bowel and malabsorption.
Prolonged antibiotics; nutrition; monitor relapse/endocarditis/CNS
Early diagnosis; prolonged treatment.
It is recommended to visit the Gastroenterology/Infectious-disease/Rheumatology/Cardiology department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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