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Home > West Medicine > Internal Medicine > Neurology
百科

Amyotrophic lateral sclerosis

神经内科

Common symptoms

舌肌萎缩、上肢周围性瘫痪、下肢中枢性瘫痪、肌肉萎缩、吞咽困难、构音不清、呛咳、腱反射亢进、感觉障碍

The pathology of disease

Amyotrophic lateral sclerosis is progressive motor neuron disease; mixed upper/lower motor neuron signs; no sensory loss; death in 3-5 y from respiratory failure.

Symptoms

Progressive weakness; fasciculations; hyperreflexia; dysarthria; dysphagia; respiratory failure

Causes

Unknown; SOD1 (familial); motor neuron degeneration.

Treatment

Riluzole; edaravone; supportive; PEG; NIV; multidisciplinary

Dept

Neurology.

Warm reminder: Health education reference only; seek care at regular hospital.