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Home > West Medicine > Internal Medicine > Nephrology
百科

Toxic nephropathy from immunosuppressants/chemo

肾内科

Common symptoms

溶血性贫血、低血钾、脱发、血小板减少、无尿、肾损害、肾功能衰竭、膀胱纤维化、少尿、肾盂积水

The pathology of disease

Toxic nephropathy from immunosuppressive/anticancer drugs includes calcineurin inhibitor nephrotoxicity; cisplatin AKI; tumor lysis; monitor renal function.

Symptoms

Rising creatinine; AKI; electrolyte disturbance; on cyclosporine/tacrolimus/cisplatin; nephrotoxic drugs

Causes

Cyclosporine/tacrolimus; cisplatin; methotrexate; other nephrotoxic chemo; tumor lysis.

Treatment

Dose adjustment/hold; hydration; monitor levels; manage AKI; renal replacement if needed

Dept

Nephrology / oncology / transplant.

Warm reminder: Health education reference only; seek care at regular hospital.