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Home > West Medicine > Internal Medicine > Nephrology
百科

Minimal change disease

肾内科

Common symptoms

呼吸困难、腹水、肾小管萎陷、尿蛋白、低蛋白血症、氮质血症、肾病综合征、少尿、蛋白尿、低血压

The pathology of disease

Minimal change disease is nephrotic syndrome in children; normal light microscopy; podocyte foot process effacement; steroid-responsive; edema; proteinuria.

Symptoms

Nephrotic syndrome; edema; proteinuria; child; normal BP; no hematuria; steroid-responsive

Causes

Podocyte dysfunction; immune; idiopathic; children; rarely NSAID-associated (adults).

Treatment

Steroids (prednisone); salt restriction; diuretics; monitor relapses; nephrology; biopsy if atypical

Dept

Nephrology / pediatrics.

Warm reminder: Health education reference only; seek care at regular hospital.