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Home > West Medicine > Internal Medicine > Hematology

Classroom classification

百科

Hypereosinophilic syndrome

血液科

Common symptoms

疲劳、嗜酸性粒细胞增多、胸痛、心力衰竭、体重减轻、肾损害、乏力、气短、心悸

The pathology of disease

Idiopathic hypereosinophilic syndrome is persistent eosinophilia >1500 with organ damage (heart/endocardium, brain, skin); males; imatinib if FIP1L1-PDGFRA.

Symptoms

Fatigue; cough; rash; heart failure; neurological; persistent eosinophilia; organ damage; male

Causes

Clonal eosinophilia; FIP1L1-PDGFRA; idiopathic; reactive vs clonal.

Treatment

Steroids; imatinib if FIP1L1-PDGFRA; hydroxyurea; mepolizumab; cardiac monitoring

Dept

Hematology / oncology / cardiology.

Warm reminder: Health education reference only; seek care at regular hospital.

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