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Home > West Medicine > Internal Medicine > Hematology

Classroom classification

百科

Hemolytic uremic syndrome

血液科

Common symptoms

昏迷、出血倾向、面色苍白、血尿、衣玉品、腹痛、氮质血症、代超、少尿、蛋白尿、急性溶血性尿毒综合征

The pathology of disease

Hemolytic uremic syndrome is triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury; post-diarrheal E. coli O157:H7 (children) vs atypical; supportive/plasma exchange.

Symptoms

Bloody diarrhea; pallor; decreased urine; bruising; AKI; child; after E. coli; MAHA smear

Causes

Shiga toxin E. coli O157:H7 (typical); complement dysregulation (atypical).

Treatment

Supportive; dialysis; plasma exchange for atypical; eculizumab for atypical; avoid antibiotics/anti-diarrheals in typical

Dept

Nephrology / pediatrics / hematology / infectious disease.

Warm reminder: Health education reference only; seek care at regular hospital.

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