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Home > West Medicine > Internal Medicine > Hematology
百科

Adult-type chronic myeloid leukemia

血液科

Common symptoms

淋巴结肿大、骨痛、阴茎异常、乏力、低热、溶骨性损害、肝脏肿大、嗜酸细胞增加

The pathology of disease

Adult-type chronic myeloid leukemia is BCR-ABL myeloproliferative neoplasm; chronic/accelerated/blast; imatinib/TKI; excellent chronic phase control; monitor molecular response.

Symptoms

Fatigue; splenomegaly; incidental high WBC; adults; BCR-ABL; Philadelphia chromosome; chronic phase

Causes

BCR-ABL translocation; Philadelphia; CML.

Treatment

Tyrosine kinase inhibitors (imatinib/dasatinib); excellent control; transplant for blast; monitor MRD; hematology

Dept

Hematology / oncology.

Warm reminder: Health education reference only; seek care at regular hospital.