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Home > West Medicine > Internal Medicine > Hematology
C95.700x003

Leukemia Cutis

血液科

Common symptoms

阴部溃疡、丘疹、结节、齿龈炎

The pathology of disease

Leukemia cutis is a malignant white-cell neoplasm; immature WBCs diffusely infiltrate marrow and appear abnormally in blood; also widely infiltrate liver/spleen/nodes and other organs including skin. Clinically specific lesions: macules, papules, plaques, nodules, ecchymoses, palpable purpura. Histology: atypical WBCs perivascular/periglandular dense or diffuse infiltrate, with subepidermal Grenz zone. Diagnosis based on predominant cell type + infiltration pattern + clinical/hematologic correlation; morphology alone insufficient; cytochemistry/IHC needed to determine origin.

Common Symptoms

Genital ulcer; papule; nodule; gingivitis

Causes and Pathogenesis

(1) Etiology: unknown. (2) Mechanism: unknown. Two types: (a) myelocytic/granulocytic leukemia; (b) AML ~50% of acute myeloid leukemias, but skin infiltration rare (5/877 AML cases).

Treatment

Drug, radiation, supportive therapy

Preventive Measures

Watch for infection; early treatment.

Department to Visit

It is recommended to visit the Hematology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.