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Home > West Medicine > Internal Medicine > Hematology
D59.101

Autoimmune Hemolytic Anemia

血液科

Common symptoms

免疫力下降、气滞血瘀、腰背酸痛、血红蛋白尿、气短、头晕、腰膝酸软、免疫性溶血、蛋白尿

The pathology of disease

Autoimmune hemolytic anemia (AIHA) is a group of anemias caused by overactive B lymphocytes producing anti-self-RBC antibodies that increase RBC destruction. Sometimes RBC destruction is compensated by marrow erythropoiesis and no anemia occurs clinically - called autoimmune hemolysis (AIH). Some patients have only detectable anti-RBC antibodies without hemolysis.

Common Symptoms

Anemia; jaundice; splenomegaly; dark urine

Causes and Pathogenesis

Autoantibodies (IgG/IgM) bind RBC antigens, causing complement activation or splenic macrophage destruction. Primary (idiopathic) or secondary to lymphoma, CLL, SLE, infection, drugs.

Treatment

Corticosteroids, immunosuppressants, transfusion, splenectomy

Preventive Measures

Treat underlying disease; avoid known drug triggers; monitor CBC.

Department to Visit

It is recommended to visit the Hematology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.