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Home > West Medicine > Internal Medicine > Rheumatology
百科

Lupus-like syndrome

风湿免疫科

Common symptoms

肝脾肿大、疲乏、呼吸困难、肌痛、咯血、甲下出血、呼吸音减弱

The pathology of disease

Lupus-like (drug-induced lupus) syndrome is anti-histone + symptoms caused by drugs (procainamide/hydralazine/isoniazid/minocycline); mild; resolves after stopping drug.

Symptoms

Arthralgia; serositis; fever; rash; after new drug; anti-histone; no severe renal/CNS involvement; resolves after stopping

Causes

Drugs: procainamide, hydralazine, isoniazid, minocycline, anti-TNF; anti-histone.

Treatment

Stop offending drug; NSAIDs/steroids; resolves in weeks; rheumatology

Dept

Rheumatology / internal medicine.

Warm reminder: Health education reference only; seek care at regular hospital.

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