Restless Legs Syndrome (RLS)

Restless legs syndrome (Willis-Ekbom disease) is a sensorimotor disorder characterized by an urge to move the legs, usually accompanied by uncomfortable sensations, worse during rest/inactivity and in the evening/night, and relieved by movement. It causes sleep disturbance. Secondary causes include iron deficiency, renal failure, pregnancy, and medications. Treatment: iron repletion if deficient; dopamine agonists or gabapentin-enacarbil; avoid triggers (caffeine/antidepressants).

Common Symptoms

Urge to move legs; uncomfortable leg sensations; worse at rest/evening; relieved by movement; sleep disturbance

Causes and Pathogenesis

Central dopaminergic dysfunction with brain iron deficiency; secondary factors (iron deficiency/renal failure/pregnancy/meds).

Treatment

Iron repletion if deficient; dopamine agonists; gabapentin-enacarbil; avoid triggers; sleep hygiene

Preventive Measures

Maintain iron stores; regular sleep; limit caffeine; treat secondary causes.

Department to Visit

It is recommended to visit the Neurology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.