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Home > West Medicine > Surgery > Orthopedics
M13.800x094

Reactive Arthritis

骨外科

Common symptoms

驻站医、肌痛、低热、肌腱端炎、骶髂关节疼痛、运动时膝前疼痛加剧

The pathology of disease

Reactive arthritis (Reiter syndrome) is post-infectious aseptic inflammatory arthritis after GU (Chlamydia trachomatis) or enteric (Salmonella/Shigella/Yersinia/Campylobacter) infection, with triad: arthritis/urethritis/conjunctivitis, HLA-B27+. Treatment: acute: NSAIDs; intra-articular corticosteroids; treat triggering infection (doxycycline/azithromycin for chlamydia + partners); sulfasalazine; methotrexate; TNF inhibitors for refractory/spondylitis; eye/GU/skin care; follow-up rheumatology/infectious disease/ophthalmology.

Common Symptoms

Asymmetric oligoarthritis; lower limbs; urethritis/conjunctivitis; enthesitis; HLA-B27

Causes and Pathogenesis

Post-infectious immune cross-reactivity (molecular mimicry) causes aseptic arthritis/enthesitis.

Treatment

NSAIDs; treat chlamydia; sulfasalazine/methotrexate; TNF inhibitors; eye/GU care

Preventive Measures

Prompt STI/GI infection treatment; safe sex; food hygiene.

Department to Visit

It is recommended to visit the Rheumatology/Infectious-disease/Ophthalmology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.