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Home > West Medicine > OB-GYN > Obstetrics
O36.001

Rh incompatibility

产科

Common symptoms

死胎、心力衰竭、嗜睡、胸腔积液、呼吸困难、腹水、抽搐、发绀、阻塞性黄疸、核黄疸

The pathology of disease

Rh blood-group antigens are determined by 3 pairs of closely linked alleles on chromosome 1, giving 6 antigens: C/c, D/d, E/e. D was discovered first and is strongest, so anyone with D is Rh-positive. Anti-d is not yet defined, so d only denotes lack of D; DD and dD are Rh-positive, dd is Rh-negative. Rh-negative frequency varies by race: ~15% in whites, 5% in US blacks, under 0.5% in Han Chinese.

Common Symptoms

Hemolytic disease, jaundice

Causes

Rh incompatibility and maternal anti-D isoimmunization.

Treatment

Anti-D prophylaxis, monitor fetus

Prevention

Anti-D immunoglobulin.

Recommended Department

It is recommended to visit the obstetrics department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.