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Home > West Medicine > OB-GYN > Gynecology
百科

Hereditary breast-ovarian cancer syndrome

妇科

Common symptoms

乳房肿块、异常子宫出血、胸痛、乏力

The pathology of disease

Hereditary breast-ovarian cancer syndrome (HBOC) is BRCA1/2 mutation; early breast/ovarian cancer; screening; risk-reducing mastectomy/oophorectomy; genetics.

Symptoms

Early breast/ovarian cancer; family history; Ashkenazi Jewish; bilateral; male breast cancer; genetic testing

Causes

BRCA1/2 mutation; autosomal dominant; DNA repair.

Treatment

Screening MRI/mammogram; risk-reducing mastectomy/oophorectomy; PARP inhibitors for cancer; genetics counseling

Dept

Genetics / breast surgery / gynecologic oncology / oncology.

Warm reminder: Health education reference only; seek care at regular hospital.