Mooren Ulcer

Mooren ulcer is a chronic, progressive, painful peripheral corneal ulceration of presumed autoimmune origin, undermining the corneal epithelium and stroma and progressing circumferentially and centrally. It is not associated with systemic disease (unlike marginal keratitis). Clinical: severe pain, redness, and progressive peripheral ulceration with overhanging edge; may perforate. Treatment: topical/systemic corticosteroids and immunosuppression (cyclosporine/MTX); conjunctival excision; tectonic keratoplasty/peritomy for perforation risk.

Common Symptoms

Severe pain; progressive peripheral ulcer with overhanging edge; redness; risk of perforation

Causes and Pathogenesis

Autoimmune attack on peripheral corneal stroma causes progressive ulceration, not linked to systemic vasculitis.

Treatment

Topical/systemic steroids + immunosuppression; conjunctival excision; tectonic keratoplasty

Preventive Measures

Immunosuppression; tectonic support.

Department to Visit

It is recommended to visit the Ophthalmology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.