Interstitial Keratitis

Interstitial keratitis is inflammation of the deep corneal stroma (without primary epithelial involvement), classically congenital syphilis but also tuberculosis, herpes, Cogan syndrome. Clinical: deep stromal vascularization (salmon patch), haze, photophobia, and reduced vision; may be bilateral. Treatment: systemic treatment of underlying cause (syphilis/TB); topical corticosteroids to reduce inflammation; corneal transplantation for dense scarring and poor vision.

Common Symptoms

Deep stromal haze/vascularization; photophobia; reduced vision; bilateral; history of syphilis/TB

Causes and Pathogenesis

Immune-mediated stromal inflammation (syphilis/TB/HPS) causes deep vascularization and scarring.

Treatment

Treat systemic cause; topical steroids; corneal transplant for dense scarring

Preventive Measures

Treat syphilis/TB; early steroids.

Department to Visit

It is recommended to visit the Ophthalmology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.