Lattice Corneal Dystrophy

Lattice corneal dystrophy is an autosomal-dominant stromal dystrophy with amyloid deposits forming lattice lines in the corneal stroma, presenting in youth with recurrent erosions and progressive visual loss. Treatment: lubrication and hypertonic agents for erosions; phototherapeutic keratectomy; corneal transplantation for significant visual loss; recurrence in grafts is common.

Common Symptoms

Recurrent erosions; lattice stromal lines; progressive visual loss; autosomal dominant, young onset

Causes and Pathogenesis

Mutated TGFBI causes amyloid deposition in the corneal stroma in a lattice pattern.

Treatment

Lubrication/hypertonic; PTK; corneal transplant for visual loss; recurrence common

Preventive Measures

Genetic counseling; manage erosions.

Department to Visit

It is recommended to visit the Ophthalmology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.