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Home > West Medicine > ENT & Ophthalmology > Ophthalmology
B30.001†

Epidemic Keratoconjunctivitis

眼科

Common symptoms

咽部充血、肌肉酸痛、上睑黄白色小点、咽痛、角膜上皮糜烂、视力障碍、流泪、结膜充血、角膜炎、角膜知觉减少

The pathology of disease

EKC is a contagious viral eye disease: acute onset, severe bilateral symptoms—congestion, pain, photophobia, watery discharge; conjunctival injection/edema/follicles; subepithelial corneal infiltrates. Caused by adenovirus (type VIII most common), epidemic-prone. Incubation 5-7 days; bilateral (one eye then the other in 2-7 days); foreign-body sensation/burning/photophobia/lacrimation/mild visual loss.

Common Symptoms

Pharyngeal injection; myalgia; yellow-white upper tarsal spots; sore throat; corneal epithelial erosion; visual disturbance; lacrimation; conjunctival injection; keratitis; reduced corneal sensation

Causes and Pathogenesis

(1) Etiology: adenovirus (DNA virus, nuclear replication; 57 serotypes, 21 human). EKC: Ad-8/19/29/37; pharyngoconjunctival fever: Ad-3/4/7; follicular conjunctivitis: Ad-1-11/14-17/19/20. Subepithelial infiltrates = immune reaction. (2) Pathogenesis: nuclear replication → direct cell injury + immune-mediated; mucosal hemorrhage/edema/exudate/infiltration; degeneration/necrosis/desquamation; inclusions.

Treatment

Drug therapy, supportive therapy

Preventive Measures

PVP-I2/PVA-I2 hand washing/soaking instruments; school/daycare/factory hygiene; Ad-8/3/11 inactivated/live attenuated vaccine (Japan).

Department to Visit

It is recommended to visit the Ophthalmology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.