Rhinoscleroma

Rhinoscleroma (scleroma) is a low-infectivity chronic granulomatous inflammation caused by Klebsiella rhinoscleromatis (Frisch bacillus). Lesions start in the nose, spread to the upper respiratory tract forming hard inflammatory masses that cause deformity or obstruction.

Common Symptoms

Dry/burning throat; dyspnea; bone lysis; olfactory disturbance; epistaxis

Causes and Pathogenesis

(1) Etiology: K. rhinoscleromatis is a Gram-negative short rod with gelatinous capsule, non-motile; transmission routes are unclear but long-term contact is common; regional prevalence (e.g., Jiaodong, China). (2) Pathogenesis: lesions start in the nose and spread upward, causing hard granulomatous masses and deformity/obstruction.

Treatment

Drug therapy, surgery, supportive therapy

Preventive Measures

Early cases are atypical; examine nasal secretions/cultures promptly. Personal hygiene; avoid shared utensils. 5% Coptis chinensis drops or 20% compound drops control disease quickly; combined with blood-activating, hardness-softening Chinese medicines for vascular complications.

Department to Visit

It is recommended to visit the ENT department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.