Juvenile Dermatomyositis

Juvenile dermatomyositis (JDM) is pediatric idiopathic inflammatory myopathy with characteristic rash (heliotrope, Gottron papules) and symmetric proximal muscle weakness. Clinical: rash, weakness, dysphagia, calcinosis, vasculitis. Diagnosis: muscle enzymes (CK, LDH, AST, ALT), EMG, MRI, biopsy; myositis-specific antibodies. Treatment: glucocorticoids (oral prednisone/IV methylprednisolone); methotrexate; IVIG; rituximab/cyclosporine for refractory; hydroxychloroquine for skin; sun protection (SPF, protective clothing); physical/occupational therapy; manage calcinosis/calcium/vitamin D; monitor growth/development; follow-up pediatric rheumatology.

Common Symptoms

Heliotrope rash; Gottron papules; proximal weakness; fatigue; dysphagia

Causes and Pathogenesis

Autoimmune microangiopathy of muscle/skin causes JDM.

Treatment

Glucocorticoids; methotrexate; IVIG; sun protection; PT

Preventive Measures

Sun protection; early diagnosis; vaccination; growth monitoring.

Department to Visit

It is recommended to visit the Pediatric-rheumatology/Dermatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.