Secondary Syphilis

Secondary syphilis is a chronic systemic STD caused by T. pallidum, mainly sexually transmitted, involving almost any organ. It causes mucocutaneous lesions and lymphadenopathy, and is transplacental causing congenital syphilis.

Common Symptoms

Macule; intercostal neuralgia; lymphadenopathy; station doctor; pustule; bone pain; fatigue; reduced immunity

Causes and Pathogenesis

Sexual contact accounts for >95% of transmission. Infectivity is highest early and declines; after >4 years it is minimal. Pregnant women transmit transplacentally causing abortion/preterm/stillbirth/congenital syphilis; earlier maternal disease = greater fetal risk, even latent syphilis is infectious. Secondary syphilis is the hematogenous dissemination phase causing widespread small foci in skin/mucosa/bones/viscera/sense organs/CNS. Symptoms appear 1 week to months after chancre. Mucocutaneous lesions contain many treponemes (highly infectious); untreated, they lay the groundwork for later visceral/neurosyphilis. Prompt adequate treatment prevents tertiary disease.

Treatment

Drug therapy, supportive therapy

Preventive Measures

1. Screen suspects with serology. 2. Isolate/treat patients; disinfect personal items.

Department to Visit

It is recommended to visit the STD department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.