Pigmented nevus

Pigmented nevus (nevocytic nevus) is a melanocytic lesion of nevus cells; the most common benign skin tumor. Almost everyone has them, anywhere on skin (face/neck most common), rarely mucosa (lip/labium/conjunctiva). Congenital or acquired; slow-growing/stable; rare spontaneous regression. Some have junctional activity and may malignant-transform. Evolution: flat junctional nevus in childhood → compound/intradermal nevus by adolescence.

Common Symptoms

Eczema; macule; papulomacular; pigmented patch; depigmentation; nodule; nevus cells

Causes

Composed of pigmented nevus cells. Origin debated: epidermal melanocytes, neural crest precursors, or dual (upper epidermis/dermis from melanocytes; lower dermis from Schwann cells). Nevus cells are nested, lack dendrites, low tyrosinase, no desmosomes; have melanocyte-like mitochondria/Golgi/melanosomes. Three basic types: junctional (at dermoepidermal junction), intradermal (within dermis), compound (both). Clinical variants: halo nevus, Spitz nevus, giant nevus, dysplastic nevus.

Treatment

No special treatment needed

Prevention

No special prevention; early detection/treatment.

Recommended Department

It is recommended to visit the dermatology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.