Malignant Blue Nevus

Malignant blue nevus is rare. Arises in pre-existing blue nevus or Ota nevus, or de novo. Superficial lesions, may ulcerate; may invade regional lymph nodes or metastasize systemically. Necrosis common; no junctional activity.

Common Symptoms

Nodule

Causes and Pathogenesis

Etiology: blue nevus = dermal melanocyte aggregation; associated with pigmented nevi, cardiac myxoma, mucocutaneous myxoma, nodular mastocytosis. Blue-gray appearance = long-wave visible light absorbed by deep dermal pigment, short blue waves reflected. 'Explosive' blue nevi linked to sun. Mechanism: melanocytes in mid-dermis, may involve upper dermis/subcutis; elongated spindle cells scattered among collagen; melanophages; ocular involvement may extend to periosteum.

Treatment

Surgery, supportive therapy

Preventive Measures

No effective prevention; early detection/diagnosis. Avoid friction/irritation of facial moles (shaving, picking); warning signs: itching, burning, enlargement, darkening, infection, ulceration, bleeding.

Department to Visit

It is recommended to visit the Dermatology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.