Parkinson Disease Dementia

Parkinson disease dementia (PDD) is dementia that develops in a patient with established Parkinson disease, typically years after motor onset, characterized by executive dysfunction, slowed thinking, visual hallucinations, fluctuations, and sleep disturbance. It is related to DLBD/Lewy-body pathology. Treatment: cholinesterase inhibitors (rivastigmine), adjust dopaminergic therapy to minimize psychosis, and supportive care; avoid antipsychotics except quetiapine/clozepine cautiously.

Common Symptoms

Executive dysfunction; slowed thinking; visual hallucinations; fluctuations; REM-behavior disorder; established parkinsonism before dementia

Causes and Pathogenesis

Lewy-body pathology extends from brainstem to cortex in long-standing PD, producing the dementia syndrome.

Treatment

Cholinesterase inhibitors; balance dopaminergic therapy; avoid typical antipsychotics; supportive care

Preventive Measures

Manage PD; monitor cognition; caregiver support.

Department to Visit

It is recommended to visit the Neurology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.