Dermatofibroma

Dermatofibroma includes soft and hard types; the hard type is a benign dermal tumor of focal fibroblast/histiocyte proliferation. Any age, middle-aged most common, female > male.

Common Symptoms

Papule; nodule; round/oval papule; firm nodule

Causes

Unknown; possibly minor trauma (insect bite/blunt injury) or viral. Ackerman considers it reactive. EM shows immature mastocytes adjacent to fibroblasts with dilated rough ER. Dermal, unencapsulated, poorly demarcated; lower border clear, upper border separated from epidermis by a grenz zone; gray-white/yellow-brown/black-brown cut. Histology: fibroblasts/histiocytes/endothelial cells/collagen; dilated capillaries; foam cells; hemosiderin; epidermal acanthosis. Two types: fibrous (most, spindle fibroblasts + collagen) and cellular (histiocytoma, histiocytes, little collagen).

Treatment

Drug therapy; surgery; supportive care

Prevention

Avoid infection/radiation/toxins; exercise; don't scratch insect bites; hygiene.

Recommended Department

It is recommended to visit the oncological surgery department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.