Choriocarcinoma

Choriocarcinoma is a highly malignant tumor following mole/abortion/full-term delivery; incidence 0.0001-0.36%; reproductive-age women; rare ectopic. Primary ovarian choriocarcinoma in virginal women. Much improved prognosis with chemotherapy. Uterine tumors are 2-10 cm, dark red/purple/brown, hemorrhagic/necrotic, friable; tumor thrombi in uterine veins; ovarian theca lutein cysts.

Common Symptoms

Abortion; bloody vaginal discharge; excessive vaginal bleeding

Causes

Related to pregnancy (mole/abortion/term); rare primary from gestational products in teratoma/tubal/abdominal pregnancy. No connective tissue stroma; only trophoblastic cells/blood clots/necrosis; no native vessels; tumor cells directly contact maternal blood. No villous structure; sheets of trophoblasts.

Treatment

Drug therapy; surgery; radiotherapy; supportive care

Prevention

Family planning/sex education; post-abortion pathology. Consolidation chemo 1-3 courses; weekly beta-HCG; re-consolidate at 3 and 6 months; no chemo after 2 years NED. Strict contraception 2 years. Malignant transformation of benign trophoblastic disease 10-20%; follow at least 2 years.

Recommended Department

It is recommended to visit the oncology department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.