Hemangioendothelioma

Hemangioendothelioma (angiosarcoma/endothelial sarcoma) is a rare malignant bone vascular tumor. Defined as irregular anastomosing vascular channels lined by atypical endothelial cells with anaplastic/immature tumor cells. 0.1-0.4% of bone tumors, 0.5-1% of malignant bone tumors, 4.2% of primary spinal tumors. Male > female; 70% age 10-40. Solitary; long bones; rare spine. High-grade, rapid, early lung metastasis.

Common Symptoms

Vascular proliferation; vascular sclerosis

Causes

No exact cause. Dark red, unencapsulated, firm, vascular; anastomosing vascular channels lined by single/multiple layers of atypical immature cells; low-differentiation/anaplastic foci; endothelial budding/papillary projections; proliferating capillaries anastomosing.

Treatment

Drug therapy; supportive care

Prevention

Adjust daily activities; regular exercise; avoid fatigue.

Recommended Department

It is recommended to visit the oncological surgery department; before the visit you may first book an appointment and connect with experts through this platform.

Warm reminder: The above information is provided for health education reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek care at a regular hospital in time.