Malignant Parotid Tumor

Malignant parotid tumor: arises from parotid acinar/ductal epithelium; mucoepidermoid carcinoma, malignant mixed tumor, adenoid cystic carcinoma, adenocarcinoma = 80-90%.

Common Symptoms

Brain metastasis; facial nerve palsy; nodule; slow growth; squamous cell carcinoma

Causes and Pathogenesis

(1) Mucoepidermoid carcinoma: from ductal epithelium; epidermoid/mucous/intermediate cells; high-grade (low differentiation) vs low-grade (high differentiation); unencapsulated/infiltrative. (2) Adenoid cystic carcinoma (cylindroma): basaloid polygonal cells; cribriform/trabecular; hyalinized stroma. (3) Malignant mixed tumor/carcinoma ex pleomorphic adenoma: benign + malignant components; transition zones; necrosis/hemorrhage/dystrophic calcification/ossification/hyalinization/infiltration = malignant signs. (4) Adenocarcinoma (NOS): intercalated duct reserve cells; hard unencapsulated mass; tubular/glandular; high-grade. (5) Acinic cell carcinoma: 7.2-19%; superficial lobe/tail; low-grade; hard lobulated; granular/vacuolated cells; small central nuclei. (6) Squamous cell carcinoma: from ductal metaplasia or ex-mixed tumor; high-grade.

Treatment

Surgical, drug, supportive therapy

Preventive Measures

Exercise; avoid acidic body; balanced lifestyle; no over-salty/spicy food; no expired food; stop smoking/alcohol.

Department to Visit

It is recommended to visit the Surgical Oncology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.