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Home > West Medicine > Internal Medicine > Respiratory Medicine
B38.200

Pulmonary Coccidioidomycosis

呼吸内科

Common symptoms

菌血症、淋巴结肿大、呼吸衰竭、低热

The pathology of disease

Coccidioidomycosis is pulmonary/systemic fungal disease by Coccidioides immitis; lung = portal and most affected organ. Primary = acute self-limited respiratory; progressive = chronic often fatal systemic.

Common Symptoms

Fungemia; lymphadenopathy; respiratory failure; low fever

Causes and Pathogenesis

Dimorphic: arthrospore in nature, spherule in host; resistant to dryness/UV, sensitive to formaldehyde; 60°C/1 h kills. Inhaled arthrospores replicate in alveoli → neutrophilic inflammation → chronic granuloma. Cell-mediated immunity; racial/ABO predisposition (Black/Native American; B/AB). Pathology: pyogenic + granulomatous alternating.

Treatment

Drug, supportive, surgical therapy

Preventive Measures

Avoid endemic areas.

Department to Visit

It is recommended to visit the Respiratory department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.