医
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淋巴结肿大、呼吸困难、低热、发绀
Pulmonary sporotrichosis is chronic pulmonary fungal disease by Sporothrix schenckii; common deep mycosis.
Lymphadenopathy; dyspnea; low fever; cyanosis
(1) Etiology: S. schenckii (Fungi/Deuteromycotina/Hyphomycetes/Moniliales), dimorphic. (2) Pathogenesis: granulomatous skin/mucosal/lymphatic; pulmonary = segmental bronchitis/bronchopneumonia; nonspecific inflammation with neutrophils/lymphocytes/plasma cells/epithelioid cells; chronic non-specific granuloma → nodular pneumonia. Typical lesions: central purulent microabscesses (neutrophils + histiocytes/lymphocytes) → epithelioid/multinucleated giant cells → lymphocytes/fibroblasts. PAS after amylase: 4-6 µm round/oval bodies; cigar bodies 4-8 µm and asteroid bodies.
Drug therapy, supportive therapy
Oral itraconazole first-line (replaces long-course KI); IV amphotericin B for systemic disease; bacterial superinfection can be fatal.
It is recommended to visit the Respiratory department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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