Subacute Infective Endocarditis

Subacute infective endocarditis is indolent infection (usually viridans streptococci) on previously abnormal valves (rheumatic/congenital/prosthetic), presenting over weeks with low-grade fever, weight loss, fatigue, anemia, and embolic/immunologic phenomena (Osler nodes, Roth spots). Treatment: blood cultures; prolonged IV bactericidal antibiotics (penicillin/ceftriaxone plus gentamicin); surgery for heart failure, persistent infection, large vegetations, or prosthetic involvement; long-term follow-up.

Common Symptoms

Low-grade fever; weight loss/fatigue; abnormal valves; embolic/immunologic signs; positive blood cultures

Causes and Pathogenesis

Viridans streptococci (dental source) indolently infect abnormal valves, causing vegetations/emboli.

Treatment

Blood cultures; prolonged IV antibiotics; surgery for HF/persistent infection/large vegetations; follow-up

Preventive Measures

Dental prophylaxis for high-risk valves; good oral hygiene.

Department to Visit

It is recommended to visit the Cardiology/Infectious-disease department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.