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Home > West Medicine > Internal Medicine > Cardiology
I42.300x012

Loffler Endocarditis

心内科

Common symptoms

收缩期反流性杂音、淋巴结肿大、肝脾肿大、心窝部隐痛、肺淤血、浅表淋巴结肿大、血栓脱落、胃肠道症状

The pathology of disease

Loffler endocarditis (eosinophilic endomyocardial disease) is endomyocardial fibrosis with eosinophilic infiltration, usually associated with hypereosinophilic syndrome, presenting with restrictive heart failure and mural thrombosis. Treatment: treat underlying eosinophilia; corticosteroids; anticoagulation; heart-failure therapy; surgical endocardiectomy for advanced restrictive disease.

Common Symptoms

Restrictive heart failure; eosinophilia; mural thrombus; systemic emboli

Causes and Pathogenesis

Eosinophilic infiltration causes endomyocardial necrosis, thrombosis, and fibrosis.

Treatment

Treat eosinophilia; steroids; anticoagulation; HF therapy; endocardiectomy for advanced

Preventive Measures

Control eosinophilia; anticoagulate to prevent emboli.

Department to Visit

It is recommended to visit the Cardiology/Hematology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.