医
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淋巴结肿大、丘疹、呼吸困难、腹水、乏力、恶心
Paracoccidioidomycosis (Brazilian/South American blastomycosis) is progressive fungal disease of mucocutaneous/lymph node/visceral sites by Paracoccidioides brasiliensis. Endemic Central/South America; men 20-50, coffee workers. Occurs in immunocompromised (including AIDS). Spores inhaled → yeast at 37°C → lymphohematogenous spread.
Lymphadenopathy; papule; dyspnea; ascites; fatigue; nausea
(1) Etiology: P. brasiliensis; dimorphic (yeast at 37°C, mycelial at room temp); multi-budding spores resemble Coccidioides endospores. (2) Pathogenesis: oral/mucosal/skin breaks; weakened resistance → local + lymphohematogenous visceral spread.
Drug therapy, supportive therapy
Azoles preferred; early diagnosis/treatment critical. Oral/nasal route; boost immunity; avoid endemic areas.
It is recommended to visit the Infectious Diseases department; an appointment can be booked on this platform before the visit.
Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.
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