Aspergillosis

Aspergillosis is chronic inflammatory disease of skin/nails/ear canal/orbit/bronchi/lung/bone/meninges by pathogenic Aspergillus; some aflatoxins oncogenic. Mostly exogenous: inhaled spores → pulmonary aspergillosis; hematogenous spread.

Common Symptoms

Visual disturbance; paroxysmal cough; anorexia; hemoptysis; nasal congestion; exophthalmos; rhinorrhea; chills; tachycardia; purulent discharge

Causes and Pathogenesis

(1) Etiology: 18 groups/132 species; human pathogens: A. fumigatus (most common), A. flavus/niger/terreus/nidulans/clavatus/versicolor/orzyae/glaucus/sydowii/lucidus/japonicus/amstelodami/ustus/restrictus/ficuum multiplicatus. (2) Pathogenesis: respiratory route; skin trauma; acute/chronic granulomatous disease of skin/mucosa/lung/brain/eye/ear/sinuses/GI/CNS/bone; sepsis/death; allergy; aflatoxins acute toxicity/carcinogenesis.

Treatment

Drug therapy, supportive therapy

Preventive Measures

Mask in contaminated environments; saline rinse eyes if grain enters; damp dusting; formaldehyde/peracetic acid disinfection; no moldy peanuts/fruit; monitor high-risk patients with nasal swabs/sputum cultures; antifungals if Aspergillus found.

Department to Visit

It is recommended to visit the Infectious Diseases department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.