Barrett Esophagus

Barrett esophagus is intestinal metaplasia (columnar epithelium with goblet cells) of distal esophagus due to chronic GERD, a premalignant lesion for esophageal adenocarcinoma. Treatment: PPI; endoscopic surveillance (3-5 yearly, or per dysplasia grade); endoscopic resection/ablation (RFA) for low/high-grade dysplasia; anti-reflux surgery (fundoplication) in selected; treat GERD aggressively; lifestyle; surveillance endoscopy with biopsies; early detection improves outcomes.

Common Symptoms

Chronic GERD symptoms; incidental finding; premalignant for adenocarcinoma

Causes and Pathogenesis

Chronic acid reflux causes squamous-to-columnar metaplasia with dysplasia risk.

Treatment

PPI; surveillance endoscopy; ablation/resection for dysplasia; anti-reflux surgery

Preventive Measures

Aggressive GERD control; weight loss; avoid trigger foods.

Department to Visit

It is recommended to visit the Gastroenterology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.