Mesenteric Panniculitis (Sclerosing Mesenteritis)

Mesenteric panniculitis (sclerosing mesenteritis) is chronic idiopathic inflammation/fibrosis of mesenteric adipose tissue. Clinical: abdominal pain, mass, nausea, weight loss, asymptomatic in many. Diagnosis: CT/MRI (misty mesentery), biopsy if needed. Treatment: asymptomatic: observation; mild: NSAIDs; moderate/severe: glucocorticoids, colchicine, azathioprine/methotrexate/thalidomide; surgical resection/bypass if obstruction/ischemia; follow-up gastroenterology/surgery.

Common Symptoms

Abdominal pain; mass; nausea; weight loss

Causes and Pathogenesis

Idiopathic chronic inflammation/fibrosis of mesenteric fat.

Treatment

Observation; NSAIDs; glucocorticoids; colchicine; immunosuppressants

Preventive Measures

Early imaging; follow-up; treat complications.

Department to Visit

It is recommended to visit the Gastroenterology/General-surgery department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.