Frontotemporal Dementia (FTD)

Frontotemporal dementia (FTD) is a progressive dementia due to frontal and/or temporal lobe degeneration, presenting in late middle age. Main variants: behavioral-variant FTD (disinhibition/apathy/hyperorality/compulsive behavior) and primary progressive aphasia (nonfluent or semantic). Memory/spatial function are relatively spared early. There is no disease-modifying therapy; treatment is supportive, with management of behavioral symptoms and caregiver support.

Common Symptoms

Early behavioral change (disinhibition/apathy/hyperorality); progressive aphasia; relative memory sparing; late-middle-age onset

Causes and Pathogenesis

Tau or TDP-43 proteinopathy causes frontal/temporal lobe degeneration, producing behavioral/language-dominant dementia.

Treatment

Supportive; manage behavioral symptoms; caregiver support; speech therapy

Preventive Measures

Supportive care; behavioral management; caregiver support.

Department to Visit

It is recommended to visit the Neurology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.