Dementia with Lewy Bodies (DLB)

Dementia with Lewy bodies (DLB) is a neurodegenerative dementia characterized by fluctuating cognition, detailed visual hallucinations, and parkinsonism, with REM-sleep behavior disorder and neuroleptic sensitivity. It overlaps with Parkinson disease dementia. Treatment: cholinesterase inhibitors for cognition/psychosis; manage parkinsonism cautiously; avoid typical antipsychotics (severe sensitivity); supportive care.

Common Symptoms

Fluctuating cognition; detailed visual hallucinations; parkinsonism; REM-sleep behavior disorder; neuroleptic sensitivity

Causes and Pathogenesis

Cortical Lewy-body (alpha-synuclein) pathology causes fluctuating cognition + visual hallucinations + parkinsonism.

Treatment

Cholinesterase inhibitors; manage parkinsonism cautiously; avoid typical antipsychotics; supportive care

Preventive Measures

Avoid antipsychotics; cholinesterase inhibitors; caregiver support.

Department to Visit

It is recommended to visit the Neurology department; an appointment can be booked on this platform before the visit.

Warm reminder: The above information is for health science reference only and cannot replace professional medical diagnosis. If you have related symptoms, please seek medical attention at a regular hospital promptly.